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This summary of lessons draws from several decades of CDA Collaborative Learning Projects’ efforts to diffuse the Do No Harm (DNH) Framework as widely as possible and to support its application and integration by humanitarian and development actors. This brief paper recounts the range of methods used, their successes, and challenges. The lessons outlined in this paper are relevant to organizations in the aid sector that focus on changing norms, practices and policies in an effort to improve the processes and results of their support to local actors and communities in conflict- , disaster-and poverty-affected contexts.